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Physical stability and release properties of lumefantrine amorphous solid dispersion granules prepared by a simple solvent evaporation approach

Amorphous solid dispersions (ASDs) of lumefantrine, which has low aqueous solubility, have been shown to improve bioavailability relative to crystalline formulations. Herein, the crystallization tendency and release properties of a variety of lumefantrine ASD granules, formed on a blend of microcrys...

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Detalhes bibliográficos
Publicado no:Int J Pharm X
Main Authors: Trasi, Niraj S., Bhujbal, Sonal V., Zemlyanov, Dmitry Y., Zhou, Qi (Tony), Taylor, Lynne S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390794/
https://ncbi.nlm.nih.gov/pubmed/32760909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpx.2020.100052
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