Physical stability and release properties of lumefantrine amorphous solid dispersion granules prepared by a simple solvent evaporation approach

Amorphous solid dispersions (ASDs) of lumefantrine, which has low aqueous solubility, have been shown to improve bioavailability relative to crystalline formulations. Herein, the crystallization tendency and release properties of a variety of lumefantrine ASD granules, formed on a blend of microcrys...

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Bibliografski detalji
Izdano u:Int J Pharm X
Glavni autori: Trasi, Niraj S., Bhujbal, Sonal V., Zemlyanov, Dmitry Y., Zhou, Qi (Tony), Taylor, Lynne S.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390794/
https://ncbi.nlm.nih.gov/pubmed/32760909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpx.2020.100052
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