Water-Induced Phase Separation of Spray-Dried Amorphous Solid Dispersions

[Image: see text] Spray drying is widely used in the manufacturing of amorphous solid dispersion (ASD) systems due to its fast drying rate, enabling kinetic trapping of the drug in amorphous form. Spray-drying conditions, such as solvent composition, can have a profound impact on the properties of s...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Li, Na, Cape, Jonathan L., Mankani, Bharat R., Zemlyanov, Dmitry Y., Shepard, Kimberly B., Morgen, Michael M., Taylor, Lynne S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539301/
https://ncbi.nlm.nih.gov/pubmed/32931293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.0c00798
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