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Effect of Storage Humidity on Physical Stability of Spray-Dried Naproxen Amorphous Solid Dispersions with Polyvinylpyrrolidone: Two Fluid Nozzle vs. Three Fluid Nozzle

In a spray drying operation, a two-fluid nozzle (2FN) with a single channel is commonly used for atomizing the feed solution. However, the less commonly used three-fluid nozzle (3FN) has two separate channels, which allow spray drying of materials in two incompatible solution systems. Although amorp...

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Publicado en:Pharmaceutics
Main Authors: Bhujbal, Sonal V., Su, Yongchao, Pathak, Vaibhav, Zemlyanov, Dmitry Y., Cavallaro, Alex-Anthony, Munson, Eric J., Taylor, Lynne S., Zhou, Qi (Tony)
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8309117/
https://ncbi.nlm.nih.gov/pubmed/34371765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13071074
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