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Physical stability and release properties of lumefantrine amorphous solid dispersion granules prepared by a simple solvent evaporation approach

Amorphous solid dispersions (ASDs) of lumefantrine, which has low aqueous solubility, have been shown to improve bioavailability relative to crystalline formulations. Herein, the crystallization tendency and release properties of a variety of lumefantrine ASD granules, formed on a blend of microcrys...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Pharm X
Hauptverfasser: Trasi, Niraj S., Bhujbal, Sonal V., Zemlyanov, Dmitry Y., Zhou, Qi (Tony), Taylor, Lynne S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390794/
https://ncbi.nlm.nih.gov/pubmed/32760909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpx.2020.100052
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