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Amorphous solid dispersion formation via solvent granulation – A case study with ritonavir and lopinavir

Herein, we evaluate the potential of using a simple solvent granulation process to prepare a binary drug amorphous solid dispersion (ASD) containing two anti-HIV drugs, ritonavir and lopinavir. The drugs were granulated onto a mixture of lactose and microcrystalline cellulose, followed by drying to...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Int J Pharm X
Päätekijät: Trasi, Niraj S., Bhujbal, Sonal, Zhou, Qi Tony, Taylor, Lynne S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880113/
https://ncbi.nlm.nih.gov/pubmed/31788669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpx.2019.100035
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