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Amorphous solid dispersion formation via solvent granulation – A case study with ritonavir and lopinavir
Herein, we evaluate the potential of using a simple solvent granulation process to prepare a binary drug amorphous solid dispersion (ASD) containing two anti-HIV drugs, ritonavir and lopinavir. The drugs were granulated onto a mixture of lactose and microcrystalline cellulose, followed by drying to...
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| Publicat a: | Int J Pharm X |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6880113/ https://ncbi.nlm.nih.gov/pubmed/31788669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpx.2019.100035 |
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