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Replicational Dilution of H3K27me3 in Mammalian Cells and the Role of Poised Promoters
Polycomb repressive complex 2 (PRC2) places H3K27me3 at developmental genes and is causally implicated in keeping bivalent genes silent. It is unclear if that silence requires minimum H3K27me3 levels and how the mark transmits faithfully across mammalian somatic cell generations. Mouse intestinal ce...
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| Veröffentlicht in: | Mol Cell |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7376365/ https://ncbi.nlm.nih.gov/pubmed/32027840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.01.017 |
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