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Poised chromatin in the mammalian germ line

Poised (bivalent) chromatin is defined by the simultaneous presence of histone modifications associated with both gene activation and repression. This epigenetic feature was first observed at promoters of lineage-specific regulatory genes in embryonic stem cells in culture. More recent work has show...

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Библиографические подробности
Главные авторы: Lesch, Bluma J., Page, David C.
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197577/
https://ncbi.nlm.nih.gov/pubmed/25249456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.113027
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