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The Ligand Binding Domain of GCNF Is Not Required for Repression of Pluripotency Genes in Mouse Fetal Ovarian Germ Cells

In mice, successful development and reproduction require that all cells, including germ cells, transition from a pluripotent to a differentiated state. This transition is associated with silencing of the pluripotency genes Oct4 and Nanog. Interestingly, these genes are repressed at different develop...

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Detalhes bibliográficos
Main Authors: Okumura, Leah M., Lesch, Bluma J., Page, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676325/
https://ncbi.nlm.nih.gov/pubmed/23762465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066062
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