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Poised chromatin in the mammalian germ line

Poised (bivalent) chromatin is defined by the simultaneous presence of histone modifications associated with both gene activation and repression. This epigenetic feature was first observed at promoters of lineage-specific regulatory genes in embryonic stem cells in culture. More recent work has show...

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Detalhes bibliográficos
Main Authors: Lesch, Bluma J., Page, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197577/
https://ncbi.nlm.nih.gov/pubmed/25249456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.113027
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