DNA binds to a specific site of the adhesive blood-protein von Willebrand factor guided by electrostatic interactions

Neutrophils release their intracellular content, DNA included, into the bloodstream to form neutrophil extracellular traps (NETs) that confine and kill circulating pathogens. The mechanosensitive adhesive blood protein, von Willebrand Factor (vWF), interacts with the extracellular DNA of NETs to pot...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Sandoval-Pérez, Angélica, Berger, Ricarda M L, Garaizar, Adiran, Farr, Stephen E, Brehm, Maria A, König, Gesa, Schneider, Stefan W, Collepardo-Guevara, Rosana, Huck, Volker, Rädler, Joachim O, Aponte-Santamaría, Camilo
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Molecular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367192/
https://ncbi.nlm.nih.gov/pubmed/32496552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa466
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