DNA binds to a specific site of the adhesive blood-protein von Willebrand factor guided by electrostatic interactions

Neutrophils release their intracellular content, DNA included, into the bloodstream to form neutrophil extracellular traps (NETs) that confine and kill circulating pathogens. The mechanosensitive adhesive blood protein, von Willebrand Factor (vWF), interacts with the extracellular DNA of NETs to pot...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Sandoval-Pérez, Angélica, Berger, Ricarda M L, Garaizar, Adiran, Farr, Stephen E, Brehm, Maria A, König, Gesa, Schneider, Stefan W, Collepardo-Guevara, Rosana, Huck, Volker, Rädler, Joachim O, Aponte-Santamaría, Camilo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2020
Gaiak:
Molecular Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367192/
https://ncbi.nlm.nih.gov/pubmed/32496552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa466
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