DNA binds to a specific site of the adhesive blood-protein von Willebrand factor guided by electrostatic interactions

Neutrophils release their intracellular content, DNA included, into the bloodstream to form neutrophil extracellular traps (NETs) that confine and kill circulating pathogens. The mechanosensitive adhesive blood protein, von Willebrand Factor (vWF), interacts with the extracellular DNA of NETs to pot...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Sandoval-Pérez, Angélica, Berger, Ricarda M L, Garaizar, Adiran, Farr, Stephen E, Brehm, Maria A, König, Gesa, Schneider, Stefan W, Collepardo-Guevara, Rosana, Huck, Volker, Rädler, Joachim O, Aponte-Santamaría, Camilo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367192/
https://ncbi.nlm.nih.gov/pubmed/32496552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa466
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