DNA binds to a specific site of the adhesive blood-protein von Willebrand factor guided by electrostatic interactions

Neutrophils release their intracellular content, DNA included, into the bloodstream to form neutrophil extracellular traps (NETs) that confine and kill circulating pathogens. The mechanosensitive adhesive blood protein, von Willebrand Factor (vWF), interacts with the extracellular DNA of NETs to pot...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Sandoval-Pérez, Angélica, Berger, Ricarda M L, Garaizar, Adiran, Farr, Stephen E, Brehm, Maria A, König, Gesa, Schneider, Stefan W, Collepardo-Guevara, Rosana, Huck, Volker, Rädler, Joachim O, Aponte-Santamaría, Camilo
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Molecular Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367192/
https://ncbi.nlm.nih.gov/pubmed/32496552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa466
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