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DNA binds to a specific site of the adhesive blood-protein von Willebrand factor guided by electrostatic interactions
Neutrophils release their intracellular content, DNA included, into the bloodstream to form neutrophil extracellular traps (NETs) that confine and kill circulating pathogens. The mechanosensitive adhesive blood protein, von Willebrand Factor (vWF), interacts with the extracellular DNA of NETs to pot...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7367192/ https://ncbi.nlm.nih.gov/pubmed/32496552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa466 |
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