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Nucleosome plasticity is a critical element of chromatin liquid–liquid phase separation and multivalent nucleosome interactions

Liquid–liquid phase separation (LLPS) is an important mechanism that helps explain the membraneless compartmentalization of the nucleus. Because chromatin compaction and LLPS are collective phenomena, linking their modulation to the physicochemical features of nucleosomes is challenging. Here, we de...

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Vydáno v:Nat Commun
Hlavní autoři: Farr, Stephen E., Woods, Esmae J., Joseph, Jerelle A., Garaizar, Adiran, Collepardo-Guevara, Rosana
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129070/
https://ncbi.nlm.nih.gov/pubmed/34001913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23090-3
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