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Nucleosome plasticity is a critical element of chromatin liquid–liquid phase separation and multivalent nucleosome interactions

Liquid–liquid phase separation (LLPS) is an important mechanism that helps explain the membraneless compartmentalization of the nucleus. Because chromatin compaction and LLPS are collective phenomena, linking their modulation to the physicochemical features of nucleosomes is challenging. Here, we de...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Farr, Stephen E., Woods, Esmae J., Joseph, Jerelle A., Garaizar, Adiran, Collepardo-Guevara, Rosana
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129070/
https://ncbi.nlm.nih.gov/pubmed/34001913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23090-3
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