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Nucleosome plasticity is a critical element of chromatin liquid–liquid phase separation and multivalent nucleosome interactions

Liquid–liquid phase separation (LLPS) is an important mechanism that helps explain the membraneless compartmentalization of the nucleus. Because chromatin compaction and LLPS are collective phenomena, linking their modulation to the physicochemical features of nucleosomes is challenging. Here, we de...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Farr, Stephen E., Woods, Esmae J., Joseph, Jerelle A., Garaizar, Adiran, Collepardo-Guevara, Rosana
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129070/
https://ncbi.nlm.nih.gov/pubmed/34001913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23090-3
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