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Nucleosome plasticity is a critical element of chromatin liquid–liquid phase separation and multivalent nucleosome interactions

Liquid–liquid phase separation (LLPS) is an important mechanism that helps explain the membraneless compartmentalization of the nucleus. Because chromatin compaction and LLPS are collective phenomena, linking their modulation to the physicochemical features of nucleosomes is challenging. Here, we de...

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Pubblicato in:Nat Commun
Autori principali: Farr, Stephen E., Woods, Esmae J., Joseph, Jerelle A., Garaizar, Adiran, Collepardo-Guevara, Rosana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129070/
https://ncbi.nlm.nih.gov/pubmed/34001913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23090-3
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