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Expansion of Intrinsically Disordered Proteins Increases the Range of Stability of Liquid–Liquid Phase Separation

Proteins containing intrinsically disordered regions (IDRs) are ubiquitous within biomolecular condensates, which are liquid-like compartments within cells formed through liquid–liquid phase separation (LLPS). The sequence of amino acids of a protein encodes its phase behaviour, not only by establis...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Garaizar, Adiran, Sanchez-Burgos, Ignacio, Collepardo-Guevara, Rosana, Espinosa, Jorge R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587599/
https://ncbi.nlm.nih.gov/pubmed/33076213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25204705
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