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Age-related accumulation of de novo mitochondrial mutations in mammalian oocytes and somatic tissues
Mutations create genetic variation for other evolutionary forces to operate on and cause numerous genetic diseases. Nevertheless, how de novo mutations arise remains poorly understood. Progress in the area is hindered by the fact that error rates of conventional sequencing technologies (1 in 100 or...
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| 出版年: | PLoS Biol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7363077/ https://ncbi.nlm.nih.gov/pubmed/32667908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000745 |
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