Streamlined analysis of duplex sequencing data with Du Novo

Duplex sequencing was originally developed to detect rare nucleotide polymorphisms normally obscured by the noise of high-throughput sequencing. Here we describe a new, streamlined, reference-free approach for the analysis of duplex sequencing data. We show the approach performs well on simulated da...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Stoler, Nicholas, Arbeithuber, Barbara, Guiblet, Wilfried, Makova, Kateryna D., Nekrutenko, Anton
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
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Method
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000403/
https://ncbi.nlm.nih.gov/pubmed/27566673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1039-4
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