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Streamlined analysis of duplex sequencing data with Du Novo
Duplex sequencing was originally developed to detect rare nucleotide polymorphisms normally obscured by the noise of high-throughput sequencing. Here we describe a new, streamlined, reference-free approach for the analysis of duplex sequencing data. We show the approach performs well on simulated da...
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| Veröffentlicht in: | Genome Biol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5000403/ https://ncbi.nlm.nih.gov/pubmed/27566673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1039-4 |
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