Increased yields of duplex sequencing data by a series of quality control tools

Duplex sequencing is currently the most reliable method to identify ultra-low frequency DNA variants by grouping sequence reads derived from the same DNA molecule into families with information on the forward and reverse strand. However, only a small proportion of reads are assembled into duplex con...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:NAR Genom Bioinform
Main Authors: Povysil, Gundula, Heinzl, Monika, Salazar, Renato, Stoler, Nicholas, Nekrutenko, Anton, Tiemann-Boege, Irene
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2021
Teme:
High Throughput Sequencing Methods
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872198/
https://ncbi.nlm.nih.gov/pubmed/33575654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqab002
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