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Integration and Fixation Preferences of Human and Mouse Endogenous Retroviruses Uncovered with Functional Data Analysis
Endogenous retroviruses (ERVs), the remnants of retroviral infections in the germ line, occupy ~8% and ~10% of the human and mouse genomes, respectively, and affect their structure, evolution, and function. Yet we still have a limited understanding of how the genomic landscape influences integration...
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Veröffentlicht in: | PLoS Comput Biol |
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Hauptverfasser: | , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Public Library of Science
2016
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4911145/ https://ncbi.nlm.nih.gov/pubmed/27309962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004956 |
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