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Integration and Fixation Preferences of Human and Mouse Endogenous Retroviruses Uncovered with Functional Data Analysis

Endogenous retroviruses (ERVs), the remnants of retroviral infections in the germ line, occupy ~8% and ~10% of the human and mouse genomes, respectively, and affect their structure, evolution, and function. Yet we still have a limited understanding of how the genomic landscape influences integration...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Campos-Sánchez, Rebeca, Cremona, Marzia A., Pini, Alessia, Chiaromonte, Francesca, Makova, Kateryna D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911145/
https://ncbi.nlm.nih.gov/pubmed/27309962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004956
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