Human L1 Transposition Dynamics Unraveled with Functional Data Analysis

Long INterspersed Elements-1 (L1s) constitute >17% of the human genome and still actively transpose in it. Characterizing L1 transposition across the genome is critical for understanding genome evolution and somatic mutations. However, to date, L1 insertion and fixation patterns have not been stu...

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Bibliographic Details
Published in:Mol Biol Evol
Main Authors: Chen, Di, Cremona, Marzia A, Qi, Zongtai, Mitra, Robi D, Chiaromonte, Francesca, Makova, Kateryna D
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Discoveries
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7743743/
https://ncbi.nlm.nih.gov/pubmed/32722770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msaa194
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