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Pronounced somatic bottleneck in mitochondrial DNA of human hair
Heteroplasmy is the presence of variable mitochondrial DNA (mtDNA) within the same individual. The dynamics of heteroplasmy allele frequency among tissues of the human body is not well understood. Here, we measured allele frequency at heteroplasmic sites in two to eight hairs from each of 11 humans...
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| Publicado no: | Philos Trans R Soc Lond B Biol Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6939377/ https://ncbi.nlm.nih.gov/pubmed/31787049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2019.0175 |
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