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Efficient In Vivo Introduction of Point Mutations Using ssODN and a Co-CRISPR Approach
BACKGROUND: The generation of point mutations is a major tool for evaluating the roles of specific nucleotides or amino acids within the regulatory or functional landscape. However, examination of these mutations in vivo requires the generation of animals carrying only the relevant point mutations a...
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| 出版年: | Biol Proced Online |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7362497/ https://ncbi.nlm.nih.gov/pubmed/32684853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12575-020-00123-7 |
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