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Efficient In Vivo Introduction of Point Mutations Using ssODN and a Co-CRISPR Approach
BACKGROUND: The generation of point mutations is a major tool for evaluating the roles of specific nucleotides or amino acids within the regulatory or functional landscape. However, examination of these mutations in vivo requires the generation of animals carrying only the relevant point mutations a...
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| Vydáno v: | Biol Proced Online |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7362497/ https://ncbi.nlm.nih.gov/pubmed/32684853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12575-020-00123-7 |
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