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TRIGGERING ANAPHASE CATASTROPHE TO COMBAT ANEUPLOID CANCERS
Cancer cells are genetically unstable and often have supernumerary centrosomes. When supernumerary centrosome clustering is inhibited at mitosis, multipolar cell division is forced, triggering apoptosis in daughter cells. This proapoptotic pathway is called anaphase catastrophe. Cyclin-dependent kin...
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| 發表在: | Trans Am Clin Climatol Assoc |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Clinical and Climatological Association
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7358487/ https://ncbi.nlm.nih.gov/pubmed/32675848 |
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