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Anaphase Catastrophe is a Target for Cancer Therapy

Neoplastic cells are genetically unstable. Strategies that target pathways affecting genome instability can be exploited to disrupt tumor cell growth potentially with limited consequences to normal cells. Chromosomal instability (CIN) is one type of genome instability characterized by mitotic defect...

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Detalhes bibliográficos
Main Authors: Galimberti, Fabrizio, Thompson, Sarah L., Ravi, Saranya, Compton, Duane A., Dmitrovsky, Ethan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061280/
https://ncbi.nlm.nih.gov/pubmed/21288923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-1178
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