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TRIGGERING ANAPHASE CATASTROPHE TO COMBAT ANEUPLOID CANCERS
Cancer cells are genetically unstable and often have supernumerary centrosomes. When supernumerary centrosome clustering is inhibited at mitosis, multipolar cell division is forced, triggering apoptosis in daughter cells. This proapoptotic pathway is called anaphase catastrophe. Cyclin-dependent kin...
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| Publicado no: | Trans Am Clin Climatol Assoc |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Clinical and Climatological Association
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7358487/ https://ncbi.nlm.nih.gov/pubmed/32675848 |
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