Increased chemotherapy-induced ovarian reserve loss in women with germline BRCA mutations due to oocyte deoxyribonucleic acid double strand break repair deficiency

OBJECTIVE: To assess whether woman who have BRCA mutations (WBM) experience more declines in ovarian reserve after chemotherapy treatment, as it induces oocyte death by deoxyribonucleic acid (DNA) damage, and BRCA mutations result in DNA damage repair deficiency. DESIGN: Longitudinal cohort study. S...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Fertil Steril
Egile Nagusiak: Oktay, Kutluk H., Bedoschi, Giuliano, Goldfarb, Shari B., Taylan, Enes, Titus, Shiny, Palomaki, Glenn E., Cigler, Tessa, Robson, Mark, Dickler, Maura N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7339936/
https://ncbi.nlm.nih.gov/pubmed/32331767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fertnstert.2020.01.033
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