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BRCA Mutations, DNA Repair Deficiency, and Ovarian Aging

Oocyte aging has a significant impact on reproductive outcomes both quantitatively and qualitatively. However, the molecular mechanisms underlying the age-related decline in reproductive success have not been fully addressed. BRCA is known to be involved in homologous DNA recombination and plays an...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biol Reprod
Main Authors: Oktay, Kutluk, Turan, Volkan, Titus, Shiny, Stobezki, Robert, Liu, Lin
Format: Artigo
Jezik:Inglês
Izdano: Society for the Study of Reproduction, Inc. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710189/
https://ncbi.nlm.nih.gov/pubmed/26224004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.132290
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