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BRCA-related ATM-mediated DNA double-strand break repair and ovarian aging

BACKGROUND: Oocyte aging has significant clinical consequences, and yet no treatment exists to address the age-related decline in oocyte quality. The lack of progress in the treatment of oocyte aging is due to the fact that the underlying molecular mechanisms are not sufficiently understood. BRCA1 a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Reprod Update
Hauptverfasser: Turan, Volkan, Oktay, Kutluk
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935693/
https://ncbi.nlm.nih.gov/pubmed/31822904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humupd/dmz043
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