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BRCA-related ATM-mediated DNA double-strand break repair and ovarian aging

BACKGROUND: Oocyte aging has significant clinical consequences, and yet no treatment exists to address the age-related decline in oocyte quality. The lack of progress in the treatment of oocyte aging is due to the fact that the underlying molecular mechanisms are not sufficiently understood. BRCA1 a...

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Pubblicato in:Hum Reprod Update
Autori principali: Turan, Volkan, Oktay, Kutluk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935693/
https://ncbi.nlm.nih.gov/pubmed/31822904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humupd/dmz043
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