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DNA-PKcs and ATM Co-Regulate DNA Double-Strand Break Repair
DNA double-strand breaks (DSBs) are repaired by nonhomologous end-joining (NHEJ) and homologous recombination (HR). The NHEJ/HR decision is under complex regulation and involves DNA-dependent protein kinase (DNA-PKcs). HR is elevated in DNA-PKcs null cells, but suppressed by DNA-PKcs kinase inhibito...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071034/ https://ncbi.nlm.nih.gov/pubmed/19535303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.05.006 |
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