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ATM specifically mediates repair of double-strand breaks with blocked DNA ends
Ataxia telangiectasia is caused by mutations in ATM and represents a paradigm for cancer predisposition and neurodegenerative syndromes linked to deficiencies in the DNA-damage response. The role of ATM as a key regulator of signalling following DNA double-strand breaks (DSBs) has been dissected in...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3948078/ https://ncbi.nlm.nih.gov/pubmed/24572510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4347 |
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