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ATM controls meiotic double-strand break formation

In many organisms, developmentally programmed double-strand breaks (DSBs) formed by the SPO11 transesterase initiate meiotic recombination, which promotes pairing and segregation of homologous chromosomes(1). Because every chromosome must receive a minimum number of DSBs, attention has focused on fa...

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Detalhes bibliográficos
Main Authors: Lange, Julian, Pan, Jing, Cole, Francesca, Thelen, Michael P., Jasin, Maria, Keeney, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213282/
https://ncbi.nlm.nih.gov/pubmed/22002603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10508
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