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Control of meiotic double-strand-break formation by ATM: local and global views
DNA double-strand breaks (DSBs) generated by the SPO11 protein initiate meiotic recombination, an essential process for successful chromosome segregation during gametogenesis. The activity of SPO11 is controlled by multiple factors and regulatory mechanisms, such that the number of DSBs is limited a...
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| Publié dans: | Cell Cycle |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6110601/ https://ncbi.nlm.nih.gov/pubmed/29963942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1464847 |
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