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Numerical constraints and feedback control of double-strand breaks in mouse meiosis

Different organisms display widely different numbers of the programmed double-strand breaks (DSBs) that initiate meiotic recombination (e.g., hundreds per meiocyte in mice and humans vs. dozens in nematodes), but little is known about what drives these species-specific DSB set points or the regulato...

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Detalhes bibliográficos
Main Authors: Kauppi, Liisa, Barchi, Marco, Lange, Julian, Baudat, Frédéric, Jasin, Maria, Keeney, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650225/
https://ncbi.nlm.nih.gov/pubmed/23599345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.213652.113
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