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Spo11 and the Formation of DNA Double-Strand Breaks in Meiosis
Meiotic recombination is carried out through a specialized pathway for the formation and repair of DNA double-strand breaks made by the Spo11 protein, a relative of archaeal topoisomerase VI. This review summarizes recent studies that provide insight to the mechanism of DNA cleavage by Spo11, functi...
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3172816/ https://ncbi.nlm.nih.gov/pubmed/21927624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/7050_2007_026 |
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