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NBS1 is required for SPO11-linked DNA double-strand break repair in male meiosis
DNA double-strand breaks (DSBs) pose a serious threat to genomic stability. Paradoxically, hundreds of programed DSBs are generated by SPO11 in meiotic prophase, which are exclusively repaired by homologous recombination (HR) to promote obligate crossover between homologous chromosomes. In somatic c...
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| Udgivet i: | Cell Death Differ |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7308329/ https://ncbi.nlm.nih.gov/pubmed/31965061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0493-4 |
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