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Functional characterization of the meiosis-specific DNA double-strand break inducing factor SPO-11 from C. elegans
The programmed induction of meiotic DNA double-strand breaks (DSBs) by the evolutionarily conserved SPO-11 protein, which is structurally related to archaeal Topo VIA topoisomerases, triggers meiotic recombination. Identification of several meiosis-specific factors that are required for SPO-11-media...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5443798/ https://ncbi.nlm.nih.gov/pubmed/28539630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02641-z |
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