Ovarian Aging in Women With BRCA Germline Mutations

CONTEXT: Recent clinical and laboratory studies suggested that women with BRCA mutations have lower ovarian reserve and their primordial follicle oocytes may be more prone to DNA damage; however, direct proof is lacking. OBJECTIVE: To determine whether women with germline BRCA mutations have reduced...

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Dettagli Bibliografici
Pubblicato in:J Clin Endocrinol Metab
Autori principali: Lin, Wayne, Titus, Shiny, Moy, Fred, Ginsburg, Elizabeth S., Oktay, Kutluk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2017
Soggetti:
Clinical Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630253/
https://ncbi.nlm.nih.gov/pubmed/28938488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2017-00765
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