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Increased chemotherapy-induced ovarian reserve loss in women with germline BRCA mutations due to oocyte deoxyribonucleic acid double strand break repair deficiency

OBJECTIVE: To assess whether woman who have BRCA mutations (WBM) experience more declines in ovarian reserve after chemotherapy treatment, as it induces oocyte death by deoxyribonucleic acid (DNA) damage, and BRCA mutations result in DNA damage repair deficiency. DESIGN: Longitudinal cohort study. S...

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שמור ב:

מידע ביבליוגרפי
הוצא לאור ב:	Fertil Steril
Main Authors:	Oktay, Kutluk H., Bedoschi, Giuliano, Goldfarb, Shari B., Taylan, Enes, Titus, Shiny, Palomaki, Glenn E., Cigler, Tessa, Robson, Mark, Dickler, Maura N.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	2020
נושאים:	Article
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7339936/ https://ncbi.nlm.nih.gov/pubmed/32331767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fertnstert.2020.01.033
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

Increased chemotherapy-induced ovarian reserve loss in women with germline BRCA mutations due to oocyte deoxyribonucleic acid double strand break repair deficiency

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