Direct Extracellular NAMPT Involvement in Pulmonary Hypertension and Vascular Remodeling. Transcriptional Regulation by SOX and HIF-2α

We previously demonstrated involvement of NAMPT (nicotinamide phosphoribosyltransferase) in pulmonary arterial hypertension (PAH) and now examine NAMPT regulation and extracellular NAMPT’s (eNAMPT’s) role in PAH vascular remodeling. NAMPT transcription and protein expression in human lung endothelia...

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Bibliografiska uppgifter
I publikationen:Am J Respir Cell Mol Biol
Huvudupphovsmän: Sun, Xiaoguang, Sun, Belinda L., Babicheva, Aleksandra, Vanderpool, Rebecca, Oita, Radu C., Casanova, Nancy, Tang, Haiyang, Gupta, Akash, Lynn, Heather, Gupta, Geetanjali, Rischard, Franz, Sammani, Saad, Kempf, Carrie L., Moreno-Vinasco, Liliana, Ahmed, Mohamed, Camp, Sara M., Wang, Jian, Desai, Ankit A., Yuan, Jason X.-J., Garcia, Joe G. N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Thoracic Society 2020
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328254/
https://ncbi.nlm.nih.gov/pubmed/32142369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2019-0164OC
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