Endothelial eNAMPT amplifies pre-clinical acute lung injury: efficacy of an eNAMPT-neutralising monoclonal antibody

RATIONALE: The severe acute respiratory syndrome coronavirus 2/coronavirus disease 2019 pandemic has highlighted the serious unmet need for effective therapies that reduce acute respiratory distress syndrome (ARDS) mortality. We explored whether extracellular nicotinamide phosphoribosyltransferase (...

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Publicado no:Eur Respir J
Main Authors: Quijada, Hector, Bermudez, Tadeo, Kempf, Carrie L., Valera, Daniel G., Garcia, Alexander N., Camp, Sara M., Song, Jin H., Franco, Evelyn, Burt, Jessica K., Sun, Belinda, Mascarenhas, Joseph B., Burns, Kimberlie, Gaber, Amir, Oita, Radu C., Reyes Hernon, Vivian, Barber, Christy, Moreno-Vinasco, Liliana, Sun, Xiaoguang, Cress, Anne E., Martin, Diego, Liu, Zhonglin, Desai, Ankit A., Natarajan, Viswanathan, Jacobson, Jeffrey R., Dudek, Steven M., Bime, Christian, Sammani, Saad, Garcia, Joe G.N.
Formato: Artigo
Idioma:Inglês
Publicado em: European Respiratory Society 2021
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100338/
https://ncbi.nlm.nih.gov/pubmed/33243842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.02536-2020
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