Endothelial eNAMPT amplifies pre-clinical acute lung injury: efficacy of an eNAMPT-neutralising monoclonal antibody

RATIONALE: The severe acute respiratory syndrome coronavirus 2/coronavirus disease 2019 pandemic has highlighted the serious unmet need for effective therapies that reduce acute respiratory distress syndrome (ARDS) mortality. We explored whether extracellular nicotinamide phosphoribosyltransferase (...

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Bibliografske podrobnosti
izdano v:Eur Respir J
Main Authors: Quijada, Hector, Bermudez, Tadeo, Kempf, Carrie L., Valera, Daniel G., Garcia, Alexander N., Camp, Sara M., Song, Jin H., Franco, Evelyn, Burt, Jessica K., Sun, Belinda, Mascarenhas, Joseph B., Burns, Kimberlie, Gaber, Amir, Oita, Radu C., Reyes Hernon, Vivian, Barber, Christy, Moreno-Vinasco, Liliana, Sun, Xiaoguang, Cress, Anne E., Martin, Diego, Liu, Zhonglin, Desai, Ankit A., Natarajan, Viswanathan, Jacobson, Jeffrey R., Dudek, Steven M., Bime, Christian, Sammani, Saad, Garcia, Joe G.N.
Format: Artigo
Jezik:Inglês
Izdano: European Respiratory Society 2021
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Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100338/
https://ncbi.nlm.nih.gov/pubmed/33243842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.02536-2020
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