Endothelial eNAMPT amplifies pre-clinical acute lung injury: efficacy of an eNAMPT-neutralising monoclonal antibody

RATIONALE: The severe acute respiratory syndrome coronavirus 2/coronavirus disease 2019 pandemic has highlighted the serious unmet need for effective therapies that reduce acute respiratory distress syndrome (ARDS) mortality. We explored whether extracellular nicotinamide phosphoribosyltransferase (...

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Argitaratua izan da:Eur Respir J
Egile Nagusiak: Quijada, Hector, Bermudez, Tadeo, Kempf, Carrie L., Valera, Daniel G., Garcia, Alexander N., Camp, Sara M., Song, Jin H., Franco, Evelyn, Burt, Jessica K., Sun, Belinda, Mascarenhas, Joseph B., Burns, Kimberlie, Gaber, Amir, Oita, Radu C., Reyes Hernon, Vivian, Barber, Christy, Moreno-Vinasco, Liliana, Sun, Xiaoguang, Cress, Anne E., Martin, Diego, Liu, Zhonglin, Desai, Ankit A., Natarajan, Viswanathan, Jacobson, Jeffrey R., Dudek, Steven M., Bime, Christian, Sammani, Saad, Garcia, Joe G.N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: European Respiratory Society 2021
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Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100338/
https://ncbi.nlm.nih.gov/pubmed/33243842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.02536-2020
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