Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition

Pulmonary vascular remodeling characterized by concentric wall thickening and intraluminal obliteration is a major contributor to the elevated pulmonary vascular resistance in patients with idiopathic pulmonary arterial hypertension (IPAH). Here we report that increased hypoxia-inducible factor 2α (...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Lung Cell Mol Physiol
Egile Nagusiak: Tang, Haiyang, Babicheva, Aleksandra, McDermott, Kimberly M., Gu, Yali, Ayon, Ramon J., Song, Shanshan, Wang, Ziyi, Gupta, Akash, Zhou, Tong, Sun, Xutong, Dash, Swetaleena, Wang, Zilu, Balistrieri, Angela, Zheng, Qiuyu, Cordery, Arlette G., Desai, Ankit A., Rischard, Franz, Khalpey, Zain, Wang, Jian, Black, Stephen M., Garcia, Joe G. N., Makino, Ayako, Yuan, Jason X.-J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866501/
https://ncbi.nlm.nih.gov/pubmed/29074488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00096.2017
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