Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension

Concentric lung vascular wall thickening due to enhanced proliferation of pulmonary arterial smooth muscle cells is an important pathological cause for the elevated pulmonary vascular resistance reported in patients with pulmonary arterial hypertension. We identified a differential role of mammalian...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Tang, Haiyang, Wu, Kang, Wang, Jian, Vinjamuri, Sujana, Gu, Yali, Song, Shanshan, Wang, Ziyi, Zhang, Qian, Balistrieri, Angela, Ayon, Ramon J., Rischard, Franz, Vanderpool, Rebecca, Chen, Jiwang, Zhou, Guofei, Desai, Ankit A., Black, Stephen M., Garcia, Joe G.N., Yuan, Jason X.-J., Makino, Ayako
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
PRECLINICAL RESEARCH
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314964/
https://ncbi.nlm.nih.gov/pubmed/30623134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.08.009
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