Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension

Concentric lung vascular wall thickening due to enhanced proliferation of pulmonary arterial smooth muscle cells is an important pathological cause for the elevated pulmonary vascular resistance reported in patients with pulmonary arterial hypertension. We identified a differential role of mammalian...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JACC Basic Transl Sci
Egile Nagusiak: Tang, Haiyang, Wu, Kang, Wang, Jian, Vinjamuri, Sujana, Gu, Yali, Song, Shanshan, Wang, Ziyi, Zhang, Qian, Balistrieri, Angela, Ayon, Ramon J., Rischard, Franz, Vanderpool, Rebecca, Chen, Jiwang, Zhou, Guofei, Desai, Ankit A., Black, Stephen M., Garcia, Joe G.N., Yuan, Jason X.-J., Makino, Ayako
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2018
Gaiak:
PRECLINICAL RESEARCH
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314964/
https://ncbi.nlm.nih.gov/pubmed/30623134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.08.009
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